Definitive epilation by means of Timedsurgery™
The Timed® apparatus can be used to perform definitive
epilation to raise the hair-line and increase forehead
height. Unwanted hair can also be removed definitively
from the cheeks, upper lip, chin and neck. Timedsurgery™
is able to remove all superfluous hair definitively,
regardless of colour (including white and blonde).


Definitive epilation with the Timed® apparatus. The
hairs are treated selectively and do not grow back.
Right: the patient immediately after the session.

Definitive epilation by means of the Timed® apparatus
was the first form of timed® epilation in the world. The
treated hair does not grow back because the highly
selective timedsurgical emission destroys the
germinative cells, which are located in the deep portion
of the follicle that extends from the outlet of the
sebaceous glands to the hair bulb. Programmed epilation
is the only form of rapid definitive epilation that
exists.
Using botulin to eliminate wrinkles from the
forehead and corrugator muscle
Injecting tiny amounts of botulin reduces the
motility of the frontal and glabellar muscles, making
the forehead smooth and wrinkle-free and slightly
raising the outer corners of the eyebrows. The effect
lasts six months. Botulin is also used to reduce “crow’s
feet” and lip wrinkles, to raise the commissures of the
lips, to eliminate chin wrinkles caused by excessive
muscle contraction and to reduce the folds on the neck
caused by contraction of the platysma.
Eliminating lip wrinkles by means of timedsurgical
mixed peeling
Timedsurgical mixed peeling is the technique of
choice for eliminating wrinkles of the upper and lower
lips permanently. The procedure involves timedsurgical
de-epithelialisation at 1 W and the subsequent
application of a saturated solution of resorcin.
Resorcin, which is inefficacious on intact skin, creates
a frost on the dermis and acts in a uniform manner on
the entire surface treated. The persistence of the
result is clearly indicated by the shortening of the
treated part, which means that the connective fibres are
reorganised and the skin is “rejuvenated”. After
peeling, a thin crust forms; this drops off after 7-12
days, leaving new wrinkle-free skin that is slightly
reddened. This reddening, which can easily be
camouflaged, lasts from six weeks to three and a half
months.

Timedsurgical mixed peeling is the technique of
choice for the elimination of lip wrinkles. As shown by
the photographs, the treated surface diminishes in area
and the distance between the nose and the vermilion
border is reduced. This reorganisation of the
connective fibres, which cannot be appreciably achieved
by means of physical methods (laser), indicates that the
result obtained will be persistent.

Timedsurgical mixed peeling after six weeks. In this
patient peeling was also performed on the lower lip.
The result obtained is permanent; this is indicated by
the reorganisation of the connective fibres and by the
consequent reduction of the treated surface.

Lip wrinkles permanently eliminated by means of
timedsurgical mixed peeling/de-epithelialisation at a
power of 1 W followed by the application of a resorcin
solution for 2 minutes.
Eliminating crow's feet and roughness of the lower
eyelid
Roughness of the lower eyelid and "crow's feet" can
easily be improved by means of timedsurgical mixed
peeling. This involves pulsed timedsurgical
de-epithelialisation at 2 W followed by the application
for 10 seconds of a saturated solution of resorcin
diluted with an equal amount of physiological solution.
Recently, we have also utilised timedsurgical
resurfacing at 38 W, Coag, EM 15 for
de-epithelialisation. Resurfacing is particularly
useful in those areas in which pulsed
de-epithelialisation proves difficult. After
application of the dilute solution of resorcin, a thin
crust immediately forms, which lasts from 10 to 15 days.
When the crust drops off, the skin appears younger and
smoother on account of the reorganisation of the
connective fibres in the dermis.


Timedsurgical mixed peeling of the lower lip
Botulin treatment of the chin
Wrinkles on the chin are sometimes caused by
excessive involuntary contraction of the muscles.
Botulin treatment reduces this involuntary movement and
the wrinkles disappear.
The efficacy of botulin treatment is evident from the
disappearance of the skin/muscle wrinkles in the test
performed on the left-hand half of the chin.
Injectable fillers (hyaluronic acid, collagen and
adipofilling®)
As fillers, we use substances that can be re-absorbed
and integrated, or a permanent filler obtained from the
patients themselves: adipofilling®. This filler is
obtained from the adipose tissue of the patient and is
subsequently supplemented with serum, which enhances its
survival. As a re-absorbable filler, we use hyaluronic
acid and collagen from human fibroblasts.
Removing tattoos by resurfacing
Timedsurgery™ is able to remove tattoos of any colour
in fewer sessions than laser treatment. In comparison
with laser therapy, timedsurgical resurfacing at 38 W,
Coag, EM 15 offers the advantage of being able to
programme the Timed® apparatus to the same settings for
all patients; this is because Timedsurgery™ is based on
electrical conductivity, which is practically identical
in all patients. By contrast, the effect of a laser
beam varies according to the colour of the skin.
Another major drawback to laser therapy is the fact that
light travels in a straight line and therefore, at high
power, damages the underlying tissues. By contrast, an
electric current travels over surfaces and can be
manipulated so as not to heat the underlying tissues.
The timedsurgical micro-arc fragments the pigment and
causes superficial vaporisation without heating the
dermis. This leads to rapid healing and better skin
quality and avoids the unsightly achromic scars
frequently left by laser therapy.
Tattoo situated in a region very favourable to
scarring. Achromic scars, inflammatory
hyperpigmentation and alterations of the skin texture
after a few sessions of laser therapy specifically
designed to remove tattoos.
Electrosalting
Timedsurgery™ utilises two techniques for removing
tattoos: timedsurgical resurfacing and electrosalting.
The former is more efficacious than laser therapy and
yields very good aesthetic results; the latter it is
chiefly used to eliminate tattoos from the eyebrows.
Vaporising small neoformations by means of
Timedsurgery™
Benign neoformations, such as angio-fibromas,
sebaceous hyperplasias, trico-epitheliomas, and fibromas
of the nose, can be vaporised by means of a timed®
emission from the Timed® apparatus. The programme data
are as follows: Coag, 50 W, 9 hundredths of a second, EM
15.

Treatment of acne scars on the face
The skin can be levelled by means of timedsurgical
resurfacing. Pits caused by scarring are filled with a
regenerative biological solution and the scars are
treated with adipofilling®. Adipofilling® exerts its
reparatory effect through stem cells injected
immediately below the scar tissue. This reparatory
effect is exerted during the course of a year.
Repigmentation of stable vitiligo
Stable vitiligo can be repigmented by means of one of
the Timedsurgery™ techniques, pulsed timedsurgical
de-epithelialisation at 2 or 3 W, followed by the
application of a graft of autologous keratinocytes and
melanocytes cultivated from a 1 cm² sample of pigmented
skin taken 20 days earlier.

The achromic area is de-epithelialised by means of
pulsed timedsurgical de-epithelialisation, one of the
techniques of Timedsurgery™. The dermis is integral and
perfectly suited to the attachment of a graft of
autologous keratinocytes and melanocytes.
 
After de-epithelialisation by means of the Timed®
apparatus, repigmentation occurs uniformly, even though
the hairs are white, as in this patient.
 

The stages of the procedure: pulsed
de-epithelialisation by means of the Timed® TD 50
micropulse; application of autologous keratinocytes
cultivated from a small fragment of normo-pigmented skin
taken 20 days earlier. Complete repigmentation of the
stable vitiligo.

Piebaldism can also be repigmented by means of pulsed
timedsurgical de-epithelialisation and the application
of autologous keratinocytes and melanocytes cultivated
from a 1 cm² sample of pigmented skin taken from a
normo-pigmented area 20 days earlier.
Transgenic skin transfer
Pulsed timedsurgical de-epithelialisation at 2 or 3 W
enables transgenic skin to be transferred for the
treatment of hereditary diseases such as epidermolysis
bollosa.
Application of genetically modified skin following
timedsurgical de-epithelialisation.
Medical treatment of the skin
Glycolic acid and trichloroacetic acid peeling
procedures; pyruvic acid procedures designed and
developed by) our Italo-Venezuelan friends Di Blasi;
home skin care.
Removing tattoos by means of timedsurgical
resurfacing
Timedsurgical resurfacing is able to eliminate any
tattoo, whatever colour it may be. It is a rapid
procedure, normally requiring three or four sessions
according to the depth of the pigment; this contrasts
with the 10 or more sessions required for laser therapy.
In our view, resurfacing is the method of choice, in
that it exploits the action of the timedsurgical
micro-arc; though very efficacious, this does not heat
the deep tissues of the skin. By contrast, laser
therapy, which utilises a beam travelling in a straight
line, penetrates in depth, damaging the skin and leaving
behind achromic scars. As it does not heat the dermis,
timedsurgical resurfacing enables rapid, high-quality
healing to take place without leaving achromic scars.
Another Timedsurgery™ procedure can also be used to
eliminate tattoos. This is a form of mixed peeling
which exploits timedsurgical de-epithelialisation:
electrosalting.

Eliminating tattoos by means of timedsurgical
resurfacing is rapid and does not damage the deep dermis.
After three months, the area can be re-treated. Result
after two sessions.
Before treatment of the entire tattoo is undertaken,
a timedsurgical resurfacing test is carried out; this
enables the depth of the pigment to be ascertained so
that the patient can be informed as to the course of the
treatment. The photograph shows the result of the
resurfacing test.
Tattoos of the eyebrows
Tattoos of the eyebrows can be eliminated by means of
another Timedsurgery™ technique: electrosalting. The
procedure involves de-epithelialisation at 1 W, followed
by application for one minute of sodium chloride, which
remains in place for 30 minutes before being washed off.
Timedsurgical electrosalting of a tattoo of the
eyebrows. This highly efficacious technique has the
advantage of being performed without cutting or damaging
the eyebrows.
Vaporising sebaceous hyperplasias
Sebaceous hyperplasias are vaporised, without
anaesthesia, by means of a timed® timedsurgical emission
at 9 hundredths of a second, 50 W, Coag, EM 15. No
medication is required. When the small crust drops off,
no visible sign will remain on the skin.


Timed® vaporisation of sebaceous hyperplasias
Vaporising ruby angiomas
Ruby angiomas are vaporised without anaesthesia by
means of Timedsurgery™. Program data: EM 15, Coag, 50 W,
9 hundredths of a second.


In this patient, 400 ruby angiomas were vaporised
without anaesthesia in a single session by means of the
Timed® apparatus.


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In many skin procedures, we utilise the Timed® TD 50
micropulse, which enables us to obtain results that no
other physical method can achieve, including laser
therapy. Timedsurgery™ is the most versatile physical
method available today in the fields of dermatology,
plastic and aesthetic surgery. We feel sorry for our
colleagues who, conditioned by the media, continue to
use procedures that have mediocre efficacy on the skin,
are costly, risky and cannot be standardised, as the
Timedsurgery™ procedures can. Unlike an electric current,
a light beam travels in a straight line; this is one of
the principal handicaps of laser therapy in the
dermatological field. If the laser is used to vaporise
a neoformation, the beam, which travels in a straight
line at more than 300,000 km per second, continues on
its path, thereby engendering a high risk of causing
achromic scars and damaging the underlying tissues.
Eliminating couperose
Telangiectasias of the face are eliminated by means
of Timedsurgery™. Pulsed micro-coagulations at 7 W,
5/100 of a second are applied along the course of the
small ectatic capillaries, which are thus obliterated.
If the telangiectasias can be injected, two or more
sessions of phlebotherapy with a 6%, 8% or 10 % solution
of sodium salicylate in a hydroglycerin vehicle are
carried out before the timedsurgical micro-coagulations.
Indeed, in this case the pathology is three-dimensional
and phlebotherapy, by reducing the diameter of the
non-visible vessels, enables the blood pressure on the
superficial capillary vessels to be reduced. If the
blood pressure is reduced, the micro-coagulations
applied to the ectatic capillaries will prove to have a
permanent effect. In a three-dimensional pathology, as
couperose often is, the problem cannot be solved by
using a two-dimensional method alone.


Elimination of couperose: before and after. If the
telangiectasias are injectable, a few sessions of
phlebotherapy are carried out to reduce the diameter of
the non-visible and visible vessels. Reducing the
diameter of the vessels reduces the superficial venous
hypertension. Subsequently, pulsed micro-coagulations
are applied. In this disorder, therapy only yields
long-lasting results if the treatment is
three-dimensional. Indeed, it is not possible to treat
a three-dimensional pathology with an exclusively
two-dimensional method. This concept is even more
important in the treatment of venous pathology of the
lower limbs.
Eliminating spider naevi
Spider naevi are eliminated by means of bipolar
Timedsurgery™, which is able to coagulate the ascending
artery at the origin, below the skin. The surface of the
skin remains undamaged. If the vascular formation
displays high pressure, a few drops of regenerative
solution (6% sodium salicylate in a buffered
hydroglycerin vehicle) can be injected into it.

The Timed® apparatus is able to carry out coagulation
at the origin of the ascending artery by using two
partially insulated electromaniples, without causing
skin lesions.

Spider naevus (stellate angioma) eliminated by means
of bipolar Timedsurgery™ using two partially insulated EM
10 Green electromaniples.
Eliminating epidermal patches
Lentigo simplex of the face and epidermal patches are
easily eliminated by means of timedsurgical resurfacing
at 38 W. The epidermis is very delicately coagulated
without being removed, and constitutes a protection for
the dermis. The epidermis remains incorporated within
the crust, which will drop off within a few days. Once
the crust has dropped off, a topical product to inhibit
melanogenesis (Angiovein® gel) is applied, followed by a
zinc oxide cream.

Eliminating patched from the hands
Patches on the hands can be eliminated by means of
timedsurgical resurfacing at 38 W in two sessions six
months apart. The procedure is carried out under
topical anaesthesia. The epidermis is not removed, but
left in place to protect the subsequent “restitutio ad
integrum”. A cortisone lotion is applied to the patches
treated. The patient must not wet the hands for two
days.
Patches on the hands can easily be eliminated by
means of Timedsurgery™. If they are very deep, 2
sessions will be required, 6 months apart. The
advantage of using timedsurgical resurfacing stems from
the fact that this technique exploits a micro-arc which,
unlike a light beam, does not cause dermal lesions and
is perfectly standardised. This is because electrical
conductivity is practically identical in all patients,
unlike a laser beam, which varies according to the
colour of the skin.
Eliminating dermal-epidermal patches
In dermal-epidermal patches, the pigment penetrates
into the dermis. Treatment consists of timedsurgical
de-epithelialisation at 1 W, which enables the epidermis
to be removed while conserving the integrity of the
dermal papillae. A saturated solution of resorcin is
applied to the dermis for about 20 seconds.

A dermal-epidermal patch on the nose is eliminated in
a single session by means of timedsurgical
de-epithelialisation followed by the application of a
saturated solution of resorcin for 20 seconds.
Depigmentation of normo-pigmented skin
Timedsurgical mixed peeling is able to de-pigment
normo-pigmented skin. Two treatment sessions are
performed six months apart.

Depigmentation of normo-pigmented skin in a patient
affected by generalised vitiligo.
Treating keratoses
Keratoses of the face and neck can easily be
eliminated by means of Timedsurgery™.


Eliminating keratoses by means of timedsurgical
resurfacing
Multiple small keratoses on the body can easily be
eliminated by means of timedsurgical resurfacing. The
Timed® apparatus is set to 50 W, Coag, EM 15 for the
resurfacing function. The moving tip of the
electromaniple repeatedly touches the lesion until it is
coagulated.
Timedsurgical resurfacing eliminates small keratoses
on the body without heating the underlying tissues. The
coagulated epidermis is not removed and healing is rapid.
This procedure is particularly recommended in the most
delicate regions of the body.
Timedsurgical blunt dissection of keratoses
Larger keratoses undergo blunt dissection from the
dermis. This is done by using the EM 10 White
electromaniple and programming the Timed® apparatus to a
power of 38 W in the resurfacing function in the Coag
mode. The epidermal formation is dissected from the
dermis by moving the finest part of the electromaniple
tangentially to the skin. The dermal lesion that is
left behind is modest.
Keratosis on the back removed by means of
timedsurgical resurfacing at 38 W, Coag, EM 10.
Eliminating milia
Milia can easily be removed by Timedsurgery™. A timed®
micro-incision is made in the epidermal dome of the cyst.
The Timed® TD 50 micropulse is able to create a
precise micro-incision in the epidermal dome of the cyst,
through which the cystic content is evacuated. The
incision exerts negligible pressure on the tissues; it
is precise and does not leave a scar. Imagine the same
micro-incision made by a laser beam. It would be
impossible.

Eliminating venous lakes from the lips
Timedsurgery™ can eliminate venous lakes from the lips
in a few seconds. An EM 10 Yellow electromaniple is
inserted into the venous lake, which is then coagulated
by a 10 W emission. On the following days, the patient
applies a coconut-butter cream.
 
Venous lake eliminated in a single session by means
of Timedsurgery™.
Skin angiomas
Neonatal cavernous skin angiomas regress
spontaneously in 70% of cases. When they involve the
face, however, they need to be treated. Treatment must
be non-radical, as it serves only to induce regression.
We use the Timed® apparatus to generate a bipolar
emission, which is delivered exclusively to the sessile
portion of the neoformation, above the skin plane.

Following coagulation of the protruding portion of
the angioma, a series of bipolar coagulations (14 W,
99/100 second) is applied to prompt regression. The
reconstructive capacity of the residual angiomatous
tissue itself is exploited in the process of recovering
complete integrity.
Procedures for rejuvenating and revitalising the
face and neck
Revitalisation exploits the patient's own biological
factors. The procedure is used to treat fine wrinkles
and scars; after rhinoplasty; in wrinkles on the neck
and in all facial areas in which the skin and the tissue
immediately below the skin require improvement. This
procedure often integrates adipofilling®, which in turn
integrates elasticum® face-lifting, this latter being an
ambulatory procedure that does not require blunt
dissection or visible medication.
Revitalisation of the neck begins by treating
wrinkles.
Treating atrophic scars and stretch-marks on the
abdomen, buttocks and breasts
Stretch-marks and atrophic scars can be improved by
means of adipofilling® or a biological revitalising
therapy that uses factors contained in the patient's own
blood. Small amounts of revitalising solution are
injected along the length of the lesion; alternatively,
larger amounts are injected intradermally or
subcutaneously in a web-like fashion. Treatment is
painless.
Biological stimulation of stretch-marks on the breast
by serum and collagene.
Timedsurgical resurfacing to level scars left by
surgery, acne or accidents
Uneven scars left by surgery, accidents or acne can
be levelled by means of timedsurgical resurfacing. The
procedure is efficacious and does not heat the deep
dermal tissues, unlike laser therapy, which uses a
straight light beam. Indeed, the high-frequency current
flows over the surface, while a light beam penetrates
the skin in depth and can cause undesired lesions,
especially at high power. For this reason, healing is
much more rapid and of better quality following
timedsurgical resurfacing.


Timedsurgical resurfacing is able to level
imperfections of the skin and facial scars. The
procedure does not heat of the tissues and healing is
rapid. Treatment of the scar is completed by means of
adipofilling®, revitalisation with biological material
and the use of scrubbing creams.
Vaporising small common warts
Small common warts are vaporised, without anaesthesia,
by means of a timed® timedsurgical emission at 9
hundredths of a second, 50 W, Coag, EM 15. After
vaporisation, 10% trichloroacetic acid is applied. No
medication is required. When the small crust drops off,
no visible sign will remain on the skin. After
vaporisation, 10% trichloroacetic acid is applied.
Eliminating common warts
We eliminate common warts by exploiting the antiviral
effect of the heat generated by the Timed®
apparatus at
low power – 10 or 14 W, EM 15. The tip of the
electromaniple penetrates the wart perpendicularly. To
facilitate penetration, the wart is bathed with a
physiological solution. Once the electrode tip has
penetrated the wart, a small circular movement is
carried out until the epidermal formation detaches from
the dermis. At this point, the wart, which remains
attached only by the surrounding epidermis, is removed
with scissors, and10% trichloroacetic acid is applied.
As the wart is a viral lesion, all of its components
must be treated together.

Warts are epidermal formations; when this
Timedsurgery™ technique is used, the dermis suffers
minimal lesions.
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